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D Wouters Selected Research

nolatrexed (AG337)

6/2003Thymidylate synthase inhibition triggers apoptosis via caspases-8 and -9 in both wild-type and mutant p53 colon cancer cell lines.
1/2000Differences in the induction of DNA damage, cell cycle arrest, and cell death by 5-fluorouracil and antifolates.

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D Wouters Research Topics

Disease

6Colorectal Neoplasms (Colorectal Cancer)
06/2008 - 02/2001
3Colonic Neoplasms (Colon Cancer)
06/2003 - 01/2000
3Neoplasm Metastasis (Metastasis)
03/2002 - 02/2001
2Paroxysmal Hemoglobinuria (Paroxysmal Nocturnal Hemoglobinuria)
11/2015 - 09/2015
2Inflammation (Inflammations)
11/2015 - 01/2010
2Lung Injury
11/2014 - 07/2014
2Neoplasms (Cancer)
05/2001 - 09/2000
1Ventral Hernia
01/2022
1Hernia (Hernias)
01/2022
1Infections
01/2018
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2018
1Pancytopenia
01/2018
1Systemic Lupus Erythematosus (Libman-Sacks Disease)
12/2017
1Immune System Diseases (Immune Disorders)
12/2017
1Drug-Related Side Effects and Adverse Reactions
01/2017
1Thrombosis (Thrombus)
11/2015
1Hemolysis
11/2015
1Atypical Hemolytic Uremic Syndrome
09/2015
1Pneumonia (Pneumonitis)
11/2014
1Mannose-Binding Protein Deficiency
10/2014
1Transfusion-Related Acute Lung Injury
07/2014
1Sepsis (Septicemia)
06/2012
1Necrosis
06/2011
1Rheumatoid Arthritis
06/2011
1Aortic Valve Disease
01/2010
1Aortic Diseases
01/2010
1Bacterial Infections (Bacterial Infection)
01/2010
1Squamous Cell Carcinoma of Head and Neck
09/2000

Drug/Important Bio-Agent (IBA)

7Proteins (Proteins, Gene)FDA Link
12/2017 - 01/2000
6Fluorouracil (Carac)FDA LinkGeneric
06/2008 - 01/2000
4Complement System Proteins (Complement)IBA
11/2015 - 01/2010
4Thymidylate SynthaseIBA
06/2008 - 06/2001
3Folic Acid AntagonistsIBA
06/2008 - 09/2000
2Nucleosomes (Nucleosome)IBA
11/2015 - 06/2012
2eculizumabFDA Link
11/2015 - 09/2015
2AntibodiesIBA
07/2014 - 02/2001
2nolatrexed (AG337)IBA
06/2003 - 01/2000
2fas Receptor (CD95 Antigen)IBA
03/2002 - 02/2001
2Folic Acid (Vitamin M)FDA LinkGeneric
05/2001 - 09/2000
2Pemetrexed (MTA)FDA Link
05/2001 - 01/2000
1LectinsIBA
01/2018
1Asparaginase (Elspar)FDA Link
01/2018
1Complement C4 (Complement Component 4)IBA
12/2017
1Pharmaceutical PreparationsIBA
01/2017
1Heme (Haem)IBA
11/2015
1Peptide Hydrolases (Proteases)FDA Link
11/2015
1CytokinesIBA
07/2014
1Complement C3a (Complement 3a)IBA
07/2014
1LipopolysaccharidesIBA
07/2014
1lipoprotein-associated coagulation inhibitor (TFPI)IBA
06/2012
1Tumor Necrosis Factor InhibitorsIBA
06/2011
1Adalimumab (Humira)FDA Link
06/2011
1N 30IBA
01/2010
1Complement Inactivating AgentsIBA
01/2010
1thiamine triphosphorate (TTP)IBA
06/2001
1Thymidine KinaseIBA
05/2001
1ThymidineIBA
05/2001
1Fas Ligand Protein (Fas Ligand)IBA
02/2001
1Caspase 3 (Caspase-3)IBA
02/2001
1FluorodeoxyuridylateIBA
09/2000
1EnzymesIBA
09/2000

Therapy/Procedure

3Therapeutics
01/2018 - 10/2014
1Operative Surgical Procedures
01/2022
1Preoperative Exercise
01/2022
1Positive-Pressure Respiration (Positive End-Expiratory Pressure)
11/2014
1Artificial Respiration (Mechanical Ventilation)
11/2014
1Drug Therapy (Chemotherapy)
06/2003